On Thursday O’Reilly laid off 21 employees at its Sebastopol, CA headquarters and more throughout the company. The local paper says “the cuts affected almost 14 percent the company’s 222 employees.” Spokesperson Sara Winge says “we’re being hit by the economic malaise.” She indicates that “the Digital Media branch was restructured into one publishing division along with the company’s Missing Manual group, O’Reilly Technology Exchange and its Head First series.” The report says the company had sales of about $70 million in 2007.Press Democrat